The cold - could it become less common?

GettyImages-177347179

The common cold is caused by a family of viruses with hundreds of variants, making it almost impossible to become immune to or vaccinate against all of them. It targets a protein in human cells, known as N-myristoyltransferase (NMT), that viruses steal from human cells to create their protective capsid by preventing any fatty-acid attachment.

In over half of cases, common colds are caused by rhinoviruses, a family of viruses with over 100 different ever-evolving variants.

Researchers at Imperial College in London are developing a way to outsmart the common cold virus by using a molecule that doesn't target the virus at all. The researchers believe that it could work against other related viruses, including those responsible for polio and foot-and-mouth disease.

The new treatment worked within minutes on human lung cells and research leader Professor Ed Tate said he was "optimistic" his team have finally found a cure. To top it all, the viruses develop quickly which is why they tend to gain resistance to any drugs rapidly.

For these reasons, most cold remedies rely on treating the symptoms of the infection - such as runny nose, sore throat and fever - rather than tackling the virus itself.


The viruses can not become resistant to the molecule because it targets the human protein and not the virus. The researchers have made a molecule that has shown to the ability to block the multiple strains of the most common cold virus, rhinovirus.

The research, published in the Nature Chemistry journal today, states the latest step to combat the common cold.

The Imperial College researchers reported that IMP-1088 blocked the common cold without affecting healthy cells.

"We haven't done any animal studies, and we obviously haven't done any studies in humans, so I can't tell you formally what the animal toxicity of this compound is", Solari says.

"A drug like this could be extremely beneficial if given early in infection, and we are working on making a version that could be inhaled so that it gets to the lungs quickly", he added.

Related News:



Most liked

OPPO's Realme 1 smartphone launched for Rs. 8990
The entry-level 3GB RAM with 32GB storage will be priced at Rs 8,990 and the 4GB RAM with 64GB storage priced at Rs 10,990. The background processes are automatically shut down to save the battery as the processor learns user's usage habits.

Mario Tennis Aces Demo Will Be Playable June 1-3
In the trailer, we see some sort of dark energy taking over Luigi, and it seems that it has already taken over Wario and Waluigi. Mario titles, perhaps especially Mario sports titles, aren't exactly renowned for their narrative prowess.

Driver: Tesla's Autopilot engaged during Utah crash
A Tesla Model S driver was travelling at 60mph (97kph) when the vehicle smashed into a fire engine in Utah on Friday night. Two people died in that incident, although the NTSB does not believe that Tesla's semi-autonomous system was to blame.

HP Expands on latest HP Elite 1000 and HP ENVY Products
The HP EliteBook x360 1030 G3, Elite x2 1013 G3, and EliteBook 1050 G1 will arrive in July, with each starting at £1,199. The company promises that it is ideal for the front desk, and other office spaces or meetings rooms.

70 officers escort slain officer's son as he returns to school
Footage shows Dakota Pitts walking with a police past a line of his father's colleagues, who stand solemnly, to the school gates. A "blue line" of support helped an IN boy go back to school, after his police officer father was killed on the job.

Incredible breakthrough shows transfer of memories possible
Adding RNA from a marine snail that was not given the tail shocks did not produce this increased excitability in sensory neurons. But scientists have been studying sea snails for a long time, and they know an terrible lot about how the organisms learn.

Pakistan collapse gives Ireland hope of remarkable Test victory
Ireland´s Kevin O´Brien celebrates his century during play on day four of Ireland´s inaugural test match against Pakistan . He was back on the field before the interval but did not bowl again in Monday's first session.

Kamal Haasan invites MK Stalin for May 19 Cauvery meet
The court intends to to end a long-running dispute that has often sparked violence. The draft proposes a 9-member authority headed by a chairman.

NASA's next Mars rover mission to carry tiny helicopter
NASA considers the mission "a high-risk, high-reward project" and if it fails, it doesn't impact the rest of the rover's mission. To deliver soil samples from the surface of the red planet, developing a complex chain of engineering solutions .

Marvel: Muslim Superhero Ms. Marvel May Get Film Soon
Marvel Studios boss Kevin Feige hinted that a movie of teen superhero Kamala Khan - aka Ms Marvel - is "in the works". " Ms. Priyanka has already voiced the role of Ms Marvel in the 2016 mobile game Marvel: Avengers Academy.

Satellite Photos Show North Korea Razing Nuclear Test Site, Analysts Say
The reporters will then be transported by a chartered train to the nuclear test site in Punggye-ri. It will be the first time that leaders of the United States and North Korea have met in person.

Honor 10 launched: Watch unboxing and first impressions
The smartphone features the trendy notched display at the top but retains a chin at the bottom to adjust the fingerprint scanner. I'm a little less enamoured with the software, however, which I cover in detail on the next page of this Honor 10 review.

Mauricio Pochettino: Spurs must take risks to win trophies
But Pochettino replied: "First of all I need to speak to Daniel and the club". I think the style of play is something that suits me and the players we have.

NBC To Debut 3 New Shows In September, 8 For The Season
Crews joined NBC's entertainment chairman, Robert Greenblatt , in saying that the show made more sense on NBC's line-up. Here lately, the Fox network has been booting many of its television shows, from The Exorcist to The Last Man on Earth .

Russia, Iran discuss nuclear deal after U.S. withdrawal
In a tweet on Sunday, Trump wrote: "Remember how badly Iran was behaving with the Iran Deal in place". They were trying to take over the Middle East by whatever means necessary.